CompPASS quantifies the extent to which each protein is enriched in each IP, relative to a larger collection of AP-MS datasets targeting unrelated baits, based on peptide abundance, frequency, and reproducibility in technical replicates. High confidence candidate interacting proteins (HCIP’s) are identified using the Normalized Weighted D-Score (NWD-Score) and Z-Score.

The link below provides access to an R implementation of the compPASS algorithm

To run compPASS in the browser, click the link below